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SIGNA MAGNUS is GE HealthCare’s premium 3.0T head-only MRI system engineered specifically for advanced neuroimaging and neuroscience discovery. Its innovative asymmetric HyperG gradient technology delivers an exceptional 300 mT/m and 750 T/m/s, enabling ultra-high b-value diffusion, short-TE imaging and detailed investigation of brain microstructure and microvasculature. Combined with AIR™ Recon DL and advanced diffusion technologies such as ODEN, SIGNA MAGNUS provides a powerful platform for neurological, neuro-oncological and neuroscience research, helping researchers explore new imaging biomarkers and advance the understanding of complex brain disorders.
SIGNA MAGNUS is GE HealthCare’s premium 3.0T dedicated head-only MRI system, specifically engineered for advanced neurological imaging, neuroscience research, and biomarker discovery. Rather than using a conventional whole-body gradient system, MAGNUS employs an innovative asymmetric head-only gradient design that enables exceptionally high gradient performance while maintaining access to the patient’s head.
Key Features
- Dedicated Head-Only 3.0T MRI: Designed specifically for high-end brain and neurological imaging rather than general whole-body MRI.
- HyperG Gradients: Delivers an exceptional 300 mT/m gradient amplitude and 750 T/m/s slew rate, substantially exceeding conventional whole-body MRI gradient performance.
- Asymmetric Gradient Design: The gradient isocenter is shifted toward the patient’s head, allowing the system to achieve extremely high gradient performance while avoiding conventional shoulder-width limitations.
- Advanced Diffusion Imaging: High gradient strength enables extremely high b-values, short echo times (TEs), and advanced diffusion techniques for investigating brain microstructure.
- ODEN — Oscillating Diffusion Encoding: Enables advanced investigation of tissue microstructure and microvasculature, supporting next-generation neuroscience and oncology research.
- AIR™ Recon DL: Deep-learning reconstruction technology designed to improve image sharpness and SNR while reducing noise and supporting efficient acquisition.
- High-Resolution Neuroimaging: Designed to visualize fine anatomical structures, brain microstructure, microvasculature and functional characteristics in exceptional detail.
- Upgradeable Platform: GE states that selected GE HealthCare 3.0T whole-body MRI systems can be upgraded to SIGNA MAGNUS, potentially reducing capital requirements for institutions already operating compatible systems.
Clinical & Research Applications
Neurology & Neuroscience
- High-resolution structural brain imaging
- Advanced diffusion imaging
- Brain microstructure characterization
- Neurodegenerative disease research
- Psychiatric disorder research
- Functional brain imaging
- Brain connectivity and network research
Neuro-Oncology
- Advanced tumor characterization
- Microstructural assessment
- Diffusion-based investigation
- Research into new imaging biomarkers
Advanced Research
SIGNA MAGNUS is particularly focused on translational neuroscience research, enabling researchers to investigate parameters and biomarkers that may be difficult or impossible to obtain using conventional whole-body MRI systems.
GE highlights applications involving brain function, microstructure and microvasculature, with the potential to translate research findings into future clinical applications.
Benefits
- Exceptional gradient performance — 300 mT/m and 750 T/m/s.
- Ultra-high diffusion capability for advanced microstructural imaging.
- Short TE and high b-value imaging for greater sensitivity to tissue microstructure.
- Exceptional brain detail for advanced neurological research.
- Advanced AI reconstruction with AIR Recon DL.
- Specialized neuroimaging platform optimized specifically for the brain.
- Potential for new biomarker discovery in neurological, oncological and psychiatric diseases.
- Upgrade pathway from selected GE 3.0T whole-body systems.
- Enables research capabilities beyond what is typically achievable with conventional 1.5T/3T whole-body MRI.
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